Rapamycin reduces testicular ischemia-reperfusion injury by enhancing autophagy
Zhi Hu, Qiong Cheng ... Wei Zhang
To confirm the effects of autophagy on testicular ischemia-reperfusion (I/R) injury.
Methods Forty rats were divided into sham group, I/R group, I/R+Rap (rapamycin, autophagy activator) group and I/R+ 3-MA (3-methyl adenine, autophagy inhibitor) group. Before inducing ischemia, rapamycin and 3-MA were intraperitoneally injected into I/R+Rap and I/R+ 3-ma groups, respectively. Subsequently, we the...
RESEARCH | Published: 17 May 2024
Asia-Pacific Journal of Pharmacotherapy & Toxicology, Articles, Volume 4 (2024)