Table of Contents

• Prospects of universal influenza virus vaccine and the current challenges of new antiviral drugs

  Samer K Almadar, Nasser M Alqahtani

  The profound impact of influenza viruses on human health persists as a significant burden, given their potent capacity to cause morbidity and mortality. Despite efforts to mitigate the annual burden of influenza, the effectiveness of current seasonal vaccines in providing substantial protection falls short, leaving undesirable pandemic of influenza viruses. The challenges posed by the influenza pa...

  REVIEW | Published: 09 Oct 2024

  Asia-Pacific Journal of Pharmacotherapy & Toxicology, Articles, Volume 4 (2024)

  Pages: 65-75   PDF(1230KB)   Views：50Downloads：1

• Recent approaches in clinical trials of hepatitis C virus vaccine, challenges and future directions

  Muhammad Shoaib Akhtar

  Globally HCV infects more than 170 million individuals and is a major risk of hepatocellular carcinoma, liver cirrhosis and transplantation. Recent antiviral therapy has significant side effects and is much expensive. During the early infection with HCV, the asymptomatic characteristics have a remarkable impact which results in unknowingly spreading HCV. Recently there is no effective vaccine ava...

  REVIEW | Published: 09 Oct 2024

  Asia-Pacific Journal of Pharmacotherapy & Toxicology, Articles, Volume 4 (2024)

  Pages: 55-64   PDF(1610KB)   Views：48Downloads：3

• Effects of xenobiotics on the blood-brain barrier and neural gene expression

  Mark Trussel, Jiff Brad

  The blood-brain barrier (BBB) is a selective barrier that restricts the entry of most substances from the bloodstream into the brain. It consists of three main components: endothelial cells, pericytes, and the astrocytic end-feet. The tight junctions (TJs) between endothelial cells contribute to the barrier's role in preventing many blood-derived substances from crossing into the brain. Xenobiotic...

  REVIEW | Published: 05 Oct 2024

  Asia-Pacific Journal of Pharmacotherapy & Toxicology, Articles, Volume 4 (2024)

  Pages: 47-54   PDF(1440KB)   Views：74Downloads：2

• Exploring pharmacist role in dispelling myths regarding covid-19 vaccination

  Ayesha Raza Butt, Hafiz Ur Rehman ... Sandal Khan

  Vaccination against Coronavirus provides adequate adaptive immunity to combat the infection. However, lack of knowledge and misinformation regarding COVID-19 vaccines leads to “Vaccine hesitancy” among people and halts the immunization process. Aim of this study is dispelling myths and misinformation via a pharmacist counseling and optimizing the vaccine acceptance to withstand this pandemic. ...

  RESEARCH | Published: 02 Mar 2024

  Asia-Pacific Journal of Pharmacotherapy & Toxicology, Articles, Volume 4 (2024)

  Pages: 1-8   PDF(774KB)   Views：449Downloads：10

• Self-medication with antibiotics and its associated factors among university students: a cross-sectional study

  Shams Ullah, Qurish Ali .... Abdul Wahid

  Self-medication is the use of medications to address self-perceived disorders or symptoms, typically without a prescription or medical oversight. Throughout the COVID-19 pandemic, there has been a notable increase in self-medication practices, particularly with antibiotics. This study is incited by the rising prevalence of antibiotic resistance and the increased antibiotic consumption observed dur...

  RESEARCH | Published: 24 Mar 2024

  Asia-Pacific Journal of Pharmacotherapy & Toxicology, Articles, Volume 4 (2024)

  Pages: 9-17   PDF(861KB)   Views：755Downloads：12

• Isolation and quantification of scopoletin from leaves and marketed formulation of morinda citrifolia L.

  K. Suresh Kumar, N. Kiruthiga ... M. Sureka

  Objective This study aims to isolate and quantify Scopoletin in leaves and commercial noni juice products of Morinda citrifolia. Methods TLC and HPTLC methods were developed for the isolation and quantification of Scopoletin. Results The ethanol leaf extract of Morinda citrifolia contains 7.4 mg of Scopoletin per 1 g of extract. Noni juices A, B, and C were found to contain 41 mg, 25.7 mg, and...

  RESEARCH | Published: 02 Jun 2024

  Asia-Pacific Journal of Pharmacotherapy & Toxicology, Articles, Volume 4 (2024)

  Pages: 18-25   PDF(1430KB)   Views：297Downloads：8